Relating to Drug: Allopurinol

HLA-B*5801 Detection
RT-PCR & SYBR Green based detection method: each sample requires only 2 PCR rxns for detecting of HLA-B*5801 and Internal Control. Analysis is based on Ct values. A complete kit version is CE marked and has IVD approval from Department of Health, Taiwan.

HLA-B*5801 Detection FastGel Test
PCR based detection method: each sample requires only 1 PCR rxn for detection of HLA-B* 5801 and Internal Control. Analysis is based on gel electrophoresis or Agilent™ BioAnalyzer™. A complete kit version is CE marked.

Product Features

• Required only hours from blood sample to results.
• Designed for easy operation & analysis.
• Validated accuracy with 600+ patients samples* & DNA sequencing.
• Protected by US, Europe & world wide patents.
• Product Sheets available in right hand column.
• Mix & Match design.

Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA-B*5801) and allopurinol induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing SJS/TEN significantly.